Non-steroidal anti-inflammatory drugs and prostaglandin effects on pepsinogen secretion by dispersed human peptic cells.

Non-steroidal anti-inflammatory drugs and prostaglandin effects on pepsinogen secretion by dispersed human peptic cells.

The effects of aspirin and ibuprofen on pepsinogen secretion were studied in isolated human peptic cells prepared from endoscopically obtained biopsy specimens after collagenase digestion, mechanical disruption, and percoll gradient centrifugation. Pharmacological concentrations of aspirin and ibuprofen (10(-8)-10(-4) M), potentiated histamine (10(-6)-10(-4)M) and forskolin (10(-5)M) stimulated...

Non-steroidal anti-inflammatory drugs and peptic ulcer.

Non-steroidal anti-inflammatory drugs have been clearly shown to increase the chances of peptic ulcer and its complications. Risk factors associated with this propensity are as yet poorly and inconsistently defined. Clinicians have long accepted that non-steroidal anti-inflammatory drug (NSAID) treatment may cause peptic ulcer and its complications. In assessing the chances it is necessary to d...

Non-steroidal anti-inflammatory drugs.

Investigation of Anti-Dermatophytic Effects of Non-Steroidal Anti-Inflammatory Drugs on Trichophyton Mentagrophytes and Epidermophyton Floccosum

Non-steroidal anti-inflammatory drugs (NSAIDs) are the most common pharmacological group that has three primary therapeutic effects including anti-inflammatory, anti-pyrexia, and analgesia. In this study, seven of NSAIDs were tested against two species of skin pathogenic fungi (dermatophytes). Percentage inhibition was determined for effective agents. Diclofenac, Aspirin and Naproxen showed muc...

Investigation of Anti-Dermatophytic Effects of Non-Steroidal Anti-Inflammatory Drugs on Trichophyton Mentagrophytes and Epidermophyton Floccosum

Non-steroidal anti-inflammatory drugs (NSAIDs) are the most common pharmacological group that has three primary therapeutic effects including anti-inflammatory, anti-pyrexia, and analgesia. In this study, seven of NSAIDs were tested against two species of skin pathogenic fungi (dermatophytes). Percentage inhibition was determined for effective agents. Diclofenac, Aspirin and Naproxen showed muc...